The 2016 premiers host the reigning champs here, in what is shaping up as the game of the round.
The Sharks will need to lift to get the win, after being beaten by Parramatta last time.
The return of favourite son Paul Gallen, as well as playing back at Shark Park will give them a big boost.
Sydney meanwhile are looking the goods once again, and will be confident of making it four straight here.
Why Sharks can win
There's plenty of positives Cronulla can take heading into this clash.
Not just Gallen but Shaun Johnson will return to the side after he was ruled out minutes before the warm-up last week with calf tightness.
At the newly re-named PointsBet Stadium, in front of a vocal Shire crowd, look for the Sharkies to give absolutely everything in their quest to stop the Chooks.
If Cronulla return to the form of two weeks ago that saw them trounce the Cowboys by 26, then they'll prove hard to beat at home.
Why Roosters can win
After their opening round loss to Souths, the Roosters have been the best team in 2019.
Luke Keary has emerged as an origin contender after stellar performances in both the number 6 and 7 jerseys, while James Tedesco and Latrell Mitchell continue to prove they are among the best backs in the league.
Last week they were close to perfect when they thumped Brisbane by 32.
With Jared Waerea-Hargreaves back after missing that game, the Roosters will only be harder to get past this time.
Only a big dip in form will see them taste defeat here.
Key NRL Stat
The Sharks have won their past 4 home games: Cronulla to win @ $2.75
NRL Betting Tip: Cronulla to cover the +6.5 point line @ $1.90
Reasoning: As good as the Roosters have been, this is a big line given the Sharks great record at home.